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CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
CD44 is a marker of tumour-initiating cells and is upregulated in invasive breast carcinoma; however, its role in the cancer progression is unknown. Here, we show that antibody-mediated CD44-targeting in human breast cancer xenografts (HBCx) significantly reduces tumour growth and that this effect i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661796/ https://ncbi.nlm.nih.gov/pubmed/19240712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604953 |
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