THE STRUCTURES OF COILED-COIL DOMAINS FROM TYPE THREE SECRETION SYSTEM TRANSLOCATORS REVEAL HOMOLOGY TO PORE-FORMING TOXINS

Many pathogenic Gram-negative bacteria utilize type III secretion systems (T3SS) to alter the normal functions of target cells. Shigella flexneri uses its T3SS to invade human intestinal cells to cause bacillary dysentery (shigellosis) which is responsible for over one million deaths per year. The S...

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Bibliographic Details
Main Authors: Barta, Michael L., Dickenson, Nicholas E., Patil, Mrinalini, Keightley, Andrew, Wyckoff, Gerald J., Picking, William D., Picking, Wendy L., Geisbrecht, Brian V.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304007/
https://ncbi.nlm.nih.gov/pubmed/22321794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.026
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