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Binding Affects the Tertiary and Quaternary Structures of the Shigella Translocator Protein IpaB and its Chaperone IpgC()

Shigella flexneri uses its type III secretion system (T3SS) to promote invasion of human intestinal epithelial cells as the first step in causing shigellosis, a life threatening form of dysentery. The Shigella type III secretion apparatus (T3SA) consists of a basal body that spans the bacterial enve...

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Bibliographic Details
Main Authors: Adam, Philip R., Patil, Mrinalini K., Dickenson, Nicholas E., Choudhari, Shyamal, Barta, Michael, Geisbrecht, Brian V., Picking, Wendy L., Picking, William D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903306/
https://ncbi.nlm.nih.gov/pubmed/22497344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300243z
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