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Lifetimes and Reaction Pathways of Guanine Radical Cations and Neutral Guanine Radicals in an Oligonucleotide in Aqueous Solutions

The exposure of guanine in the oligonucleotide 5’-d(TCGCT) to one-electron oxidants leads initially to the formation of the guanine radical cation G(•+), its deptotonation product G(−H)(•) and, ultimately, to various two- and four-electron oxidation products via pathways that depend on the oxidants...

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Autors principals: Rokhlenko, Yekaterina, Geacintov, Nicholas E., Shafirovich, Vladimir
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303975/
https://ncbi.nlm.nih.gov/pubmed/22329445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja212186w
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