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Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence

We previously reported that the frequency of polyploidy aortic vascular smooth muscle cells (VSMC) serves as a biomarker of aging. Cellular senescence of somatic cells is another marker of aging that is characterized by the inability to undergo cell division. Here, we examined whether polyploidy is...

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Autores principales: Yang, Dan, McCrann, Donald J., Nguyen, Hao, St. Hilaire, Cynthia, DePinho, Ronald A., Jones, Matthew R., Ravid, Katya
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303600/
https://ncbi.nlm.nih.gov/pubmed/17291294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00274.x
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