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Deregulated Aurora-B induced tetraploidy promotes tumorigenesis
High expression of Aurora-B has been observed in various cancers, and inhibition of this kinase has been shown to halt cellular proliferation. However, the mechanism of effect of Aurora-B on cellular transformation has not been fully explored. Here, we show that overexpression of Aurora-B in murine...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Federation of American Societies for Experimental Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717782/ https://ncbi.nlm.nih.gov/pubmed/19332642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-130963 |
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