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Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence

We previously reported that the frequency of polyploidy aortic vascular smooth muscle cells (VSMC) serves as a biomarker of aging. Cellular senescence of somatic cells is another marker of aging that is characterized by the inability to undergo cell division. Here, we examined whether polyploidy is...

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Detalhes bibliográficos
Main Authors: Yang, Dan, McCrann, Donald J., Nguyen, Hao, St. Hilaire, Cynthia, DePinho, Ronald A., Jones, Matthew R., Ravid, Katya
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303600/
https://ncbi.nlm.nih.gov/pubmed/17291294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00274.x
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