Short small-interfering RNAs produce interferon-α-mediated analgesia

BACKGROUND: There is increasing interest in RNA interference in pain research using the intrathecal route to deliver small-interfering RNA (siRNA). An interferon (IFN) response is a common side-effect of siRNA. However, the IFN response in the spinal cord after intrathecal administration of siRNA re...

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Bibliographic Details
Main Authors: Tan, P. H., Gao, Y. J., Berta, T., Xu, Z. Z., Ji, R. R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Pain
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303487/
https://ncbi.nlm.nih.gov/pubmed/22307241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aer492
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