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Probing Lactate Dehydrogenase Activity in Tumors by Measuring Hydrogen/Deuterium Exchange in Hyperpolarized l-[1-(13)C,U-(2)H]Lactate
[Image: see text] (13)C magnetic resonance spectroscopy and spectroscopic imaging measurements of hyperpolarized (13)C label exchange between exogenously administered [1-(13)C]pyruvate and endogenous lactate, catalyzed by lactate dehydrogenase (LDH), has proved to be a powerful approach for probing...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2012
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303201/ https://ncbi.nlm.nih.gov/pubmed/22316419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja300222e |
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