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Differential confounding of rare and common variants in spatially structured populations
Well-powered genome-wide association studies, now possible through advances in technology and large-scale collaborative projects, promise to reveal the contribution of rare variants to complex traits and disease. However, while population structure is a known confounder of association studies, it is...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303124/ https://ncbi.nlm.nih.gov/pubmed/22306651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.1074 |
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