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Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo

When DNA is damaged or DNA replication goes awry, cells activate checkpoints to allow time for damage to be repaired and replication to complete. In Saccharomyces cerevisiae, the DNA damage checkpoint, which responds to lesions such as double-strand breaks, is activated when the lesion promotes the...

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Autors principals: Berens, Theresa J., Toczyski, David P.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302733/
https://ncbi.nlm.nih.gov/pubmed/22298423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0852
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