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Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53
When DNA replication is stalled, a signal transduction pathway is activated that promotes the stability of stalled forks and resumption of DNA synthesis. In budding yeast, this pathway includes the kinases Mec1 and Rad53. Here we report that the Mediator protein Mrc1, which is required for normal DN...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196183/ https://ncbi.nlm.nih.gov/pubmed/12865299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1098303 |
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