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Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53
When DNA replication is stalled, a signal transduction pathway is activated that promotes the stability of stalled forks and resumption of DNA synthesis. In budding yeast, this pathway includes the kinases Mec1 and Rad53. Here we report that the Mediator protein Mrc1, which is required for normal DN...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196183/ https://ncbi.nlm.nih.gov/pubmed/12865299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1098303 |
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