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Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae

Replication fork stalling at a DNA lesion generates a damage signal that activates the Rad53 kinase, which plays a vital role in survival by stabilizing stalled replication forks. However, evidence that Rad53 directly modulates the activity of replication forks has been lacking, and the nature of fo...

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Detalhes bibliográficos
Main Authors: Szyjka, Shawn J., Aparicio, Jennifer G., Viggiani, Christopher J., Knott, Simon, Xu, Weihong, Tavaré, Simon, Aparicio, Oscar M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492737/
https://ncbi.nlm.nih.gov/pubmed/18628397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1660408
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