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Cohesin association to replication sites depends on Rad50 and promotes fork restart
The cohesin complex holds together newly-replicated chromatids and is involved in diverse pathways that preserve genome integrity. We show that in budding yeast, cohesin is transiently recruited to active replication origins and it spreads along DNA as forks progress. When DNA synthesis is impeded,...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904740/ https://ncbi.nlm.nih.gov/pubmed/22885006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.004 |
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