The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets

The route by which highly pathogenic avian influenza (HPAI) H5N1 virus spreads systemically, including the central nervous system (CNS), is largely unknown in mammals. Especially, the olfactory route, which could be a route of entry into the CNS, has not been studied in detail. Although the multibas...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Schrauwen, Eefje J. A., Herfst, Sander, Leijten, Lonneke M., van Run, Peter, Bestebroer, Theo M., Linster, Martin, Bodewes, Rogier, Kreijtz, Joost H. C. M., Rimmelzwaan, Guus F., Osterhaus, Albert D. M. E., Fouchier, Ron A. M., Kuiken, Thijs, van Riel, Debby
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302532/
https://ncbi.nlm.nih.gov/pubmed/22278228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06828-11
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker