Pathogenesis of Influenza A/H5N1 Virus Infection in Ferrets Differs between Intranasal and Intratracheal Routes of Inoculation

Most patients infected with highly pathogenic avian influenza A/H5N1 virus develop severe pneumonia resulting in acute respiratory distress syndrome, with extrarespiratory disease as an uncommon complication. Intranasal inoculation of ferrets with influenza A/H5N1 virus causes lesions in both the re...

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Detalhes bibliográficos
Main Authors: Bodewes, Rogier, Kreijtz, Joost H.C.M., van Amerongen, Geert, Fouchier, Ron A.M., Osterhaus, Albert D.M.E., Rimmelzwaan, Guus F., Kuiken, Thijs
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123863/
https://ncbi.nlm.nih.gov/pubmed/21640972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.026
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