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Phosphorylation of BRN2 Modulates Its Interaction with the Pax3 Promoter To Control Melanocyte Migration and Proliferation

MITF-M and PAX3 are proteins central to the establishment and transformation of the melanocyte lineage. They control various cellular mechanisms, including migration and proliferation. BRN2 is a POU domain transcription factor expressed in melanoma cell lines and is involved in proliferation and inv...

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Main Authors: Berlin, Irina, Denat, Laurence, Steunou, Anne-Lise, Puig, Isabel, Champeval, Delphine, Colombo, Sophie, Roberts, Karen, Bonvin, Elise, Bourgeois, Yveline, Davidson, Irwin, Delmas, Véronique, Nieto, Laurence, Goding, Colin R., Larue, Lionel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302439/
https://ncbi.nlm.nih.gov/pubmed/22290434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06257-11
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