A Phosphatidylinositol 3-Kinase–Pax3 Axis Regulates Brn-2 Expression in Melanoma

Deregulation of transcription arising from mutations in key signaling pathways is a hallmark of cancer. In melanoma, the most aggressive and lethal form of skin cancer, the Brn-2 transcription factor (POU3F2) regulates proliferation and invasiveness and lies downstream from mitogen-activated protein...

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Detaylı Bibliyografya
Asıl Yazarlar: Bonvin, Elise, Falletta, Paola, Shaw, Heather, Delmas, Veronique, Goding, Colin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486186/
https://ncbi.nlm.nih.gov/pubmed/22988297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01067-12
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