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Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination

How melanoma acquire a metastatic phenotype is a key issue. One possible mechanism is that metastasis is driven by microenvironment-induced switching between non-invasive and invasive states. However, whether switching is a reversible or hierarchical process is not known and is difficult to assess b...

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Detalhes bibliográficos
Main Authors: Pinner, Sophie, Jordan, Peter, Sharrock, Kirsty, Bazley, Laura, Collinson, Lucy, Marais, Richard, Bonvin, Elise, Goding, Colin, Sahai, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763120/
https://ncbi.nlm.nih.gov/pubmed/19826052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0781
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