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Luria-Delbrück Estimation of Turnip Mosaic Virus Mutation Rate In Vivo

A potential drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs is the ease with which viruses may generate escape mutations. Using a variation of the classic Luria-Delbrück fluctuation assay, we estimated that the spontaneous mutation rate in the artifi...

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Bibliografiset tiedot
Päätekijät: de la Iglesia, Francisca, Martínez, Fernando, Hillung, Julia, Cuevas, José M., Gerrish, Philip J., Daròs, José-Antonio, Elena, Santiago F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302333/
https://ncbi.nlm.nih.gov/pubmed/22238294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06909-11
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