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Large population solution of the stochastic Luria–Delbrück evolution model

Luria and Delbrück introduced a very useful and subsequently widely adopted framework for quantitatively understanding the emergence of new cellular lineages. Here, we provide an analytical treatment of the fully stochastic version of the model, enabled by the fact that population sizes at the time...

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Bibliographic Details
Main Authors: Kessler, David A., Levine, Herbert
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718099/
https://ncbi.nlm.nih.gov/pubmed/23818583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309667110
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