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Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process

One of the most popular models for quantitatively understanding the emergence of drug resistance both in bacterial colonies and in malignant tumors was introduced long ago by Luria and Delbrück. Here, individual resistant mutants emerge randomly during the birth events of an exponentially growing se...

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Pubblicato in:J Stat Phys
Autori principali: Kessler, David A., Levine, Herbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760705/
https://ncbi.nlm.nih.gov/pubmed/26900175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-014-1143-3
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