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Improving the Effectiveness of Artificial MicroRNA (amiR)-Mediated Resistance against Turnip Mosaic Virus by Combining Two amiRs or by Targeting Highly Conserved Viral Genomic Regions

A drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs (amiRs) is the ease with which viruses generate escape mutations. Here, we show two alternative strategies for improving the effectiveness of resistance in plants. First, we expressed two amiRs comple...

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Detalhes bibliográficos
Main Authors: Lafforgue, Guillaume, Martínez, Fernando, Niu, Qi-Wen, Chua, Nam-Hai, Daròs, José-Antonio, Elena, Santiago F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700214/
https://ncbi.nlm.nih.gov/pubmed/23698292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00914-13
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