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Improving the Effectiveness of Artificial MicroRNA (amiR)-Mediated Resistance against Turnip Mosaic Virus by Combining Two amiRs or by Targeting Highly Conserved Viral Genomic Regions

A drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs (amiRs) is the ease with which viruses generate escape mutations. Here, we show two alternative strategies for improving the effectiveness of resistance in plants. First, we expressed two amiRs comple...

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Autores principales: Lafforgue, Guillaume, Martínez, Fernando, Niu, Qi-Wen, Chua, Nam-Hai, Daròs, José-Antonio, Elena, Santiago F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700214/
https://ncbi.nlm.nih.gov/pubmed/23698292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00914-13
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