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Luria-Delbrück Estimation of Turnip Mosaic Virus Mutation Rate In Vivo
A potential drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs is the ease with which viruses may generate escape mutations. Using a variation of the classic Luria-Delbrück fluctuation assay, we estimated that the spontaneous mutation rate in the artifi...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302333/ https://ncbi.nlm.nih.gov/pubmed/22238294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06909-11 |
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