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Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity

Effective humoral responses to protein antigens require the precise execution of carefully timed differentiation programs in both T and B cell compartments. Disturbances in this process underlie the pathogenesis of many autoimmune disorders, including systemic lupus erythematosus (SLE). Interferon r...

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Bibliografische gegevens
Hoofdauteurs: Biswas, Partha S., Gupta, Sanjay, Stirzaker, Roslynn A., Kumar, Varsha, Jessberger, Rolf, Lu, Theresa T., Bhagat, Govind, Pernis, Alessandra B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302237/
https://ncbi.nlm.nih.gov/pubmed/22370718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111195
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