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Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity
Effective humoral responses to protein antigens require the precise execution of carefully timed differentiation programs in both T and B cell compartments. Disturbances in this process underlie the pathogenesis of many autoimmune disorders, including systemic lupus erythematosus (SLE). Interferon r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302237/ https://ncbi.nlm.nih.gov/pubmed/22370718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111195 |
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