Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R. N. Dubois. 1992. J. Biol. Chem. 267:21720-21726). Treatment of rats on a high salt diet with the epox...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Makita, K, Takahashi, K, Karara, A, Jacobson, H R, Falck, J R, Capdevila, J H
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7989598/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117608
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