Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R. N. Dubois. 1992. J. Biol. Chem. 267:21720-21726). Treatment of rats on a high salt diet with the epox...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Clin Invest
Päätekijät:	Makita, K, Takahashi, K, Karara, A, Jacobson, H R, Falck, J R, Capdevila, J H
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Clinical Investigation 1994
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7989598/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117608
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