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Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells

In addition to its important functions in detoxification of foreign chemicals and biosynthesis of steroid hormones, the cytochrome P450 enzyme system metabolizes arachidonate to 14,15-epoxyeicosatrienoic acid (14,15-EET). This study demonstrates that a P450 arachidonate epoxygenase metabolite can ac...

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Détails bibliographiques
Auteurs principaux: Chen, Jian-Kang, Capdevila, Jorge, Harris, Raymond C.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122896/
https://ncbi.nlm.nih.gov/pubmed/11983897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092671899
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