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Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells

In addition to its important functions in detoxification of foreign chemicals and biosynthesis of steroid hormones, the cytochrome P450 enzyme system metabolizes arachidonate to 14,15-epoxyeicosatrienoic acid (14,15-EET). This study demonstrates that a P450 arachidonate epoxygenase metabolite can ac...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chen, Jian-Kang, Capdevila, Jorge, Harris, Raymond C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092671899
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