Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells

In addition to its important functions in detoxification of foreign chemicals and biosynthesis of steroid hormones, the cytochrome P450 enzyme system metabolizes arachidonate to 14,15-epoxyeicosatrienoic acid (14,15-EET). This study demonstrates that a P450 arachidonate epoxygenase metabolite can ac...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Chen, Jian-Kang, Capdevila, Jorge, Harris, Raymond C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092671899
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