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Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns

Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells. Methods to control the cellular uptake and nuclear localization of these compounds are esse...

詳細記述

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書誌詳細
主要な著者: Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300022/
https://ncbi.nlm.nih.gov/pubmed/22080545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr970
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