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Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns
Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells. Methods to control the cellular uptake and nuclear localization of these compounds are esse...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300022/ https://ncbi.nlm.nih.gov/pubmed/22080545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr970 |
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