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Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin

Telomeres, the ends of linear chromosomes, safeguard against genome instability. The enzyme responsible for extension of the telomere 3′ terminus is the ribonucleoprotein telomerase. Whereas telomerase activity can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse t...

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Hlavní autoři: Gardano, Laura, Holland, Linda, Oulton, Rena, Le Bihan, Thierry, Harrington, Lea
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300002/
https://ncbi.nlm.nih.gov/pubmed/22187156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1243
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