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Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin
Telomeres, the ends of linear chromosomes, safeguard against genome instability. The enzyme responsible for extension of the telomere 3′ terminus is the ribonucleoprotein telomerase. Whereas telomerase activity can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse t...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300002/ https://ncbi.nlm.nih.gov/pubmed/22187156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1243 |
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