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Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin

Telomeres, the ends of linear chromosomes, safeguard against genome instability. The enzyme responsible for extension of the telomere 3′ terminus is the ribonucleoprotein telomerase. Whereas telomerase activity can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse t...

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Autori principali: Gardano, Laura, Holland, Linda, Oulton, Rena, Le Bihan, Thierry, Harrington, Lea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300002/
https://ncbi.nlm.nih.gov/pubmed/22187156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1243
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