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Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin
Telomeres, the ends of linear chromosomes, safeguard against genome instability. The enzyme responsible for extension of the telomere 3′ terminus is the ribonucleoprotein telomerase. Whereas telomerase activity can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse t...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300002/ https://ncbi.nlm.nih.gov/pubmed/22187156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1243 |
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