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Dyskerin expression correlates with active proliferation independently of telomerase

BACKGROUND: Dyskerin, which is an important component of the telomerase complex and is needed for normal telomerase activity, is frequently overexpressed in neoplasia. Dyskerin also plays an essential role in ribosome biogenesis. Since protein synthesis increases during tumorigenesis, this led us to...

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Main Authors: Alawi, Faizan, Lin, Ping, Ziober, Barry, Patel, Reena
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116033/
https://ncbi.nlm.nih.gov/pubmed/21674675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21579
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