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Dyskerin expression correlates with active proliferation independently of telomerase
BACKGROUND: Dyskerin, which is an important component of the telomerase complex and is needed for normal telomerase activity, is frequently overexpressed in neoplasia. Dyskerin also plays an essential role in ribosome biogenesis. Since protein synthesis increases during tumorigenesis, this led us to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116033/ https://ncbi.nlm.nih.gov/pubmed/21674675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21579 |
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