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Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing

Dyskerin is an essential nucleolar protein required for the biogenesis of ribonucleoproteins that incorporate H/ACA RNAs. Through binding to specific H/ACA RNAs, dyskerin exerts most of its influence in the cell. To that end, dyskerin is a core component of the telomerase complex and is required for...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Alawi, Faizan, Lin, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117972/
https://ncbi.nlm.nih.gov/pubmed/21480387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20715
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