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Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing

Dyskerin is an essential nucleolar protein required for the biogenesis of ribonucleoproteins that incorporate H/ACA RNAs. Through binding to specific H/ACA RNAs, dyskerin exerts most of its influence in the cell. To that end, dyskerin is a core component of the telomerase complex and is required for...

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Bibliografske podrobnosti
Main Authors: Alawi, Faizan, Lin, Ping
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117972/
https://ncbi.nlm.nih.gov/pubmed/21480387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20715
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