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Dyskerin Ablation in Mouse Liver Inhibits rRNA Processing and Cell Division

Dyskerin is a component of small nucleolar ribonucleoprotein complexes and acts as a pseudouridine synthase to modify newly synthesized ribosomal, spliceosomal, and possibly other RNAs. It is encoded by the DKC1 gene, the gene mutated in X-linked dyskeratosis congenita, and is also part of the telom...

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Autori principali: Ge, Jingping, Rudnick, David A., He, Jun, Crimmins, Dan L., Ladenson, Jack H., Bessler, Monica, Mason, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798470/
https://ncbi.nlm.nih.gov/pubmed/19917719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01128-09
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