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RNase MRP is required for entry of 35S precursor rRNA into the canonical processing pathway

RNase MRP is a nucleolar RNA–protein enzyme that participates in the processing of rRNA during ribosome biogenesis. Previous experiments suggested that RNase MRP makes a nonessential cleavage in the first internal transcribed spacer. Here we report experiments with new temperature-sensitive RNase MR...

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Detalhes bibliográficos
Main Authors: Lindahl, Lasse, Bommankanti, Ananth, Li, Xing, Hayden, Lauren, Jones, Adrienne, Khan, Miriam, Oni, Tolulope, Zengel, Janice M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704079/
https://ncbi.nlm.nih.gov/pubmed/19465684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1302909
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