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A Novel Model for the RNase MRP-Induced Switch between the Formation of Different Forms of 5.8S rRNA

Processing of the RNA polymerase I pre-rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs requires removing the “spacer” sequences. The canonical pathway for the removal of the ITS1 spacer involves cleavages at the 3′ end of 18S rRNA and at two sites inside ITS1. The process can generate eithe...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Li, Xiao, Zengel, Janice M., Lindahl, Lasse
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268776/
https://ncbi.nlm.nih.gov/pubmed/34206573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136690
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