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A Novel Model for the RNase MRP-Induced Switch between the Formation of Different Forms of 5.8S rRNA

Processing of the RNA polymerase I pre-rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs requires removing the “spacer” sequences. The canonical pathway for the removal of the ITS1 spacer involves cleavages at the 3′ end of 18S rRNA and at two sites inside ITS1. The process can generate eithe...

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Pubblicato in:Int J Mol Sci
Autori principali: Li, Xiao, Zengel, Janice M., Lindahl, Lasse
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268776/
https://ncbi.nlm.nih.gov/pubmed/34206573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136690
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