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Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na(+)/Ca(2+) exchanger

Glutamate-induced delayed calcium dysregulation (DCD) is a causal factor leading to neuronal death. The mechanism of DCD is not clear but Ca(2+) influx via N-methyl-D-aspartate receptors (NMDAR) and/or the reverse plasmalemmal Na(+)/Ca(2+) exchanger (NCX(rev)) could be involved in DCD. However, the...

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Detalhes bibliográficos
Main Authors: Brittain, Matthew K., Brustovetsky, Tatiana, Sheets, Patrick L., Brittain, Joel M., Khanna, Rajesh, Cummins, Theodore R., Brustovetsky, Nickolay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299854/
https://ncbi.nlm.nih.gov/pubmed/22249110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.051
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