Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via Deconjugation

BACKGROUND: Chronic oral quercetin reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (aglycone) is usually not present in plasma, because it is rapidly metabolized into conjugated, mostly inactive, metabolites. The aim of the study is to analyze...

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Hlavní autoři: Galindo, Pilar, Rodriguez-Gómez, Isabel, González-Manzano, Susana, Dueñas, Montserrat, Jiménez, Rosario, Menéndez, Carmen, Vargas, Félix, Tamargo, Juan, Santos-Buelga, Celestino, Pérez-Vizcaíno, Francisco, Duarte, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299686/
https://ncbi.nlm.nih.gov/pubmed/22427863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032673
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