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Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages

Dietary flavonoids, such as quercetin, have long been recognized to protect blood vessels from atherogenic inflammation by yet unknown mechanisms. We have previously discovered the specific localization of quercetin-3-O-glucuronide (Q3GA), a phase II metabolite of quercetin, in macrophage cells in t...

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Detalhes bibliográficos
Main Authors: Ishisaka, Akari, Kawabata, Kyuichi, Miki, Satomi, Shiba, Yuko, Minekawa, Shoko, Nishikawa, Tomomi, Mukai, Rie, Terao, Junji, Kawai, Yoshichika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834324/
https://ncbi.nlm.nih.gov/pubmed/24260490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080843
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