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Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages

Dietary flavonoids, such as quercetin, have long been recognized to protect blood vessels from atherogenic inflammation by yet unknown mechanisms. We have previously discovered the specific localization of quercetin-3-O-glucuronide (Q3GA), a phase II metabolite of quercetin, in macrophage cells in t...

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Bibliografiske detaljer
Main Authors: Ishisaka, Akari, Kawabata, Kyuichi, Miki, Satomi, Shiba, Yuko, Minekawa, Shoko, Nishikawa, Tomomi, Mukai, Rie, Terao, Junji, Kawai, Yoshichika
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834324/
https://ncbi.nlm.nih.gov/pubmed/24260490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080843
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