Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via Deconjugation

BACKGROUND: Chronic oral quercetin reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (aglycone) is usually not present in plasma, because it is rapidly metabolized into conjugated, mostly inactive, metabolites. The aim of the study is to analyze...

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Detalhes bibliográficos
Main Authors: Galindo, Pilar, Rodriguez-Gómez, Isabel, González-Manzano, Susana, Dueñas, Montserrat, Jiménez, Rosario, Menéndez, Carmen, Vargas, Félix, Tamargo, Juan, Santos-Buelga, Celestino, Pérez-Vizcaíno, Francisco, Duarte, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299686/
https://ncbi.nlm.nih.gov/pubmed/22427863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032673
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