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Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation.

Cross-linking of the surface antigen receptor on B lymphocytes has been demonstrated to lead to activation of phospholipase C (PLC) with subsequent increases in production of inositol phosphates and diacylglycerol. In turn, these second messengers increase cytosolic free calcium [( Ca2+]i) and activ...

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Detalhes bibliográficos
Main Authors: Padeh, S, Levitzki, A, Gazit, A, Mills, G B, Roifman, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329909/
https://ncbi.nlm.nih.gov/pubmed/1705565
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