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Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation.
Cross-linking of the surface antigen receptor on B lymphocytes has been demonstrated to lead to activation of phospholipase C (PLC) with subsequent increases in production of inositol phosphates and diacylglycerol. In turn, these second messengers increase cytosolic free calcium [( Ca2+]i) and activ...
Uloženo v:
| Vydáno v: | J Clin Invest |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115074 |
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