Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation.

Cross-linking of the surface antigen receptor on B lymphocytes has been demonstrated to lead to activation of phospholipase C (PLC) with subsequent increases in production of inositol phosphates and diacylglycerol. In turn, these second messengers increase cytosolic free calcium [( Ca2+]i) and activ...

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Publié dans:	J Clin Invest
Auteurs principaux:	Padeh, S, Levitzki, A, Gazit, A, Mills, G B, Roifman, C M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115074
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