Aldosterone Blunts Tubuloglomerular Feedback by Activating Macula Densa Mineralocorticoid Receptors

Chronic aldosterone administration increases glomerular filtration rate (GFR) while inhibition of mineralocorticoid receptors (MR) markedly attenuates glomerular hyperfiltration and hypertension associated with primary aldosteronism or obesity. However, the mechanisms by which aldosterone alters GFR...

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Autori principali: Fu, Yiling, Hall, John E., Lu, Deyin, Lin, Lin, Manning, R Davis, Cheng, Liang, Gomez-Sanchez, Celso E., Juncos, Luis A., Liu, Ruisheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299000/
https://ncbi.nlm.nih.gov/pubmed/22311906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.173195
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